The Gut Club’s Microbiome Vaccine Safety Project is creating new scientific research and public education. We are now on Patreon, raising funds to finance new research to explore our central hypothesis, microbial predisposition to adverse vaccine reaction.
Gut microbiota have a significant effect on host response to vaccination where a reduced or absent population of commensal flora coupled with an overgrowth of pathogenic strains may become a microbial predisposition to adverse vaccine reaction. This may include reduced or absent protective microbiota such as Bifidobacteria, Lactobacillus and butyrate-producing Clostridia allowing immune dysregulating Bacteroides and Proteobacteria to be overgrown.
In exploring this important concept, The Gut Club is working with a gnotobiotic pig laboratory:
Lijuan Yuan, PhD, Associate Professor, Virology and Immunology Department of Biomedical Sciences & Pathobiology, Virginia-Maryland College of Veterinary Medicine
We are also working with a microbiome DNA stool testing company where one goal is to conduct a routine infant meconium and stool testing demonstration project at a hospital:
Ping-Chuan Christina Tsai, PhD, Head of Research & Development, Thryve
Please share our new, peer-reviewed paper: Do gut microbiota mediate adverse vaccine reaction?
It may also be shared on Twitter from the Journal page:
This is the FIRST paper published about microbial predisposition to adverse vaccine reaction. There’s plenty of research published about microbial regulation of immune response to vaccination, including probiotic adjuvants, vaccine efficacy and failure, yet none of this research has focus on adverse reaction.
What is also significant is our laboratory partner to conduct the research.
Ideally, our goal is to combine the research project with a documentary film which will also document the research, The Science of Microbes (working title). The film will have much focus on child health including the reciprocal relationship between microbiota and host immune system. Included is a separate 30 minute documentary for children.
Thank you for your interest and support!
Here are some articles describing the hypothesis. Our new, peer-reviewed article has been approved by a medical Journal and now in press.
Facebook explorations/research: #microbiomevaccinesafetyproject