There’s so much to learn about gene-microbe interaction as root cause of autoimmunity.
I’ve barely scratched the surface. This is why everyone needs to join forces to understand this complex science. Genetic regulation of microbial populations is another underrated factor, i.e., fucose and the field of glycobiology. There’s also evidence of the immune system selecting Clostridia.
And to think this may be initiated in the fetal GI tract is a paradigm shift most scientists still refuse to accept. It’s time to take them to task.
Human gut colonisation may be initiated in utero by distinct microbial communities in the placenta and amniotic fluid
http://www.nature.com/articles/srep23129